HDAC-IN-42

• Target:

  Apoptosis|||Others|||HDAC

• Related Pathways:

  Others|||DNA Damage/DNA Repair|||Apoptosis|||Chromatin/Epigenetic

• Bioactivity:

  HDAC-IN-42 (compound 14f) is a highly potent and selective inhibitor of histone deacetylase (HDAC) enzymes, with IC50 values of 0.19 ?M for HDAC1 and 4.98 ?M for HDAC6. It exhibits significant anticancer properties, inhibiting cell proliferation, inducing apoptosis, and causing cell cycle arrest specifically at the G2/M phase [1].

• Smiles:

  C (OC1=CC (/C=C/C (NO) =O) =CC=C1) (=O) C2=CC=3C (OC2=O) =CC (OC) =CC3

• Molecular Formula:

  C20H15NO7

• Molecular Weight:

  381.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2454024-18-9