JAK-IN-21

CAT: 0931-T61494-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T61494-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2445499-20-5

Target

JAK, Tyrosine Kinases

Related Pathways

JAK/STAT signaling, Stem Cells, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.9987

Bioactivity

JAK-IN-21 is a selective and potent JAK inhibitor that inhibits JAK1, JAK2, J2V617F and TYK2 with IC50 values of 1.73, 2.04, 109 and 62.9 nM, respectively.

Smiles

CC=1C(=NC(NC2=CN(CC#N)N=C2)=NC1)C3=CC=C(C(NCC#N)=O)C=C3

Molecular Formula

C19H16N8O

Molecular Weight

372.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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