JAK-IN-5

CAT: 0804-HY-111471Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-111471Size:1 Each
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Description
JAK-IN-5 is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.
CAS Number
[2096999-92-5]
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/JAK_inhibitor_1.html
Solubility
10 mM in DMSO
Smiles
CN1CCC(N2CC(N=C(C3=NNC4=C3C=CC(C5=C(CC)C=C(O)C(F)=C5)=C4)N6)=C6CC2)CC1
Molecular Formula
C27H31FN6O
Molecular Weight
474.57
References & Citations
[1]Paul R. Fatheree, et al. JAK Kinase Inhibitor Compounds for Treatment of Respiratory Disease. US20170121327A1|[2]Venkat R, et al. Methods of treatment using a jak inhibitor compound. US20180311226.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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