JAK-IN-31

CAT: 0931-T79882-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T79882-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2597016-88-9

Target

JAK

Related Pathways

Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells, JAK/STAT signaling

Bioactivity

JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 μM for JAK1, ≤0.01 μM for JAK2, 0.01-0.1 μM for JAK3, and ≤0.01 μM for Tyk2, indicating potent activity across these targets. It is utilized in cancer research [1].

Smiles

N(C=1C(=CN=C2C1C=CN2)C=3SC(C)=NN3)[C@@H]4C[C@H](NS(=O)(=O)C5=CC(C#N)=CC=C5)C4

Molecular Formula

C21H19N7O2S2

Molecular Weight

465.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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