Trk-IN-7
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Trk-IN-7
Target:
Others|||Trk receptorRelated Pathways:
Tyrosine Kinase/Adaptors|||OthersBioactivity:
Trk-IN-7 (compound I-6) is a highly potent TRK inhibitor, with IC50 values of 0.25-10 nM for TRKA, TRKB, and TRKC, respectively. It also shows significant inhibition of EML4-ALK (IC50 <15 nM) and ALK mutations G1202R, C1156Y, R1275Q, F1174L, L1197M, and G1269A (IC50 = 5-50 nM) [1].Molecular Formula:
C18H17FN6O2Molecular Weight:
368.36Shipping Conditions:
Cool packStorage Temperature:
-20°C