17 (R) -HETE

• Target:

  Others|||Cytochromes P450

• Related Pathways:

  Others|||Metabolism

• Bioactivity:

  Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. 17 (R) -HETE is an inactive isomer of 17-HETE, whereas the (S) enantiomer can inhibit proximal tubule ATPase activity at a concentration of 2 ?M.

• Smiles:

  CCC[C@@H] (O) C\C=C/C\C=C/C\C=C/C\C=C/CCCC (O) =O

• Molecular Formula:

  C20H32O3

• Molecular Weight:

  320.473

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  183509-24-2