GNF-1331

• Target:

  Others|||Porcupine|||Wnt/beta-catenin

• Related Pathways:

  Others|||Cytoskeletal Signaling|||Stem Cells

• Bioactivity:

  GNF-1331 is a potent, selective, and orally bioavailable porcupine inhibitor (IC50 = 12 nM) . Blocking abnormal Wnt signaling is an attractive treatment for a variety of cancers.

• Smiles:

  C(CC)N1C(=NN=C1SCC(NC=2SC=3C(N2)=CC=C(OC)C3)=O)C=4C=CN=CC4

• Molecular Formula:

  C20H20N6O2S2

• Molecular Weight:

  440.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  603101-22-0