GNF-5837

• Target:

  PDGFR|||c-Kit|||Trk receptor

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity:

  0.9929

• Bioactivity:

  GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM) .

• Smiles:

  Cc1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1

• Molecular Formula:

  C28H21F4N5O2

• Molecular Weight:

  535.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1033769-28-6