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GNF-5

CAT: 0931-T1803-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T1803-01Size:1 mL - 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
778277-15-9
Target
SARS-CoV, Bcr-Abl
Related Pathways
Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Angiogenesis, Microbiology/Virology
Purity
0.9998
Bioactivity
GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22±0.1 uM, Wild-type Abl) . It is an analog of GNF-2 with improved pharmacokinetic properties.
Smiles
N(C1=CC(=NC=N1)C2=CC(C(NCCO)=O)=CC=C2)C3=CC=C(OC(F)(F)F)C=C3
Molecular Formula
C20H17F3N4O3
Molecular Weight
418.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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