SI-2

CAT: 0931-T28773-04Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T28773-04Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

223788-33-8

Target

Others, Apoptosis, Src

Related Pathways

Apoptosis, Tyrosine Kinase/Adaptors, Others, Angiogenesis

Purity

0.984

Bioactivity

SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1) . SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM), but not affect normal cell viability.

Smiles

CN1C=2C(N=C1NN=C(C)C3=CC=CC=N3)=CC=CC2

Molecular Formula

C15H15N5

Molecular Weight

265.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

1-Methyl-N-[(E)-1-pyridin-2-ylethylideneamino]benzimidazol-2-amine

CAS Number	223788-33-8
PubChem CID	10220948
IUPAC Name	1-methyl-N-[(E)-1-pyridin-2-ylethylideneamino]benzimidazol-2-amine
Molecular Formula	C15H15N5
Molecular Weight	265.31
XLogP	2.9
Topological Polar Surface Area	55.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	20
Formal Charge	0
Complexity	356

SMILES

C/C(=N\NC1=NC2=CC=CC=C2N1C)/C3=CC=CC=N3

InChI

InChI=1S/C15H15N5/c1-11(12-7-5-6-10-16-12)18-19-15-17-13-8-3-4-9-14(13)20(15)2/h3-10H,1-2H3,(H,17,19)/b18-11+

InChIKey

JNNXERNBPXXNLK-WOJGMQOQSA-N

Chemical Structure

2D Structure

CAS: 223788-33-8

CID: 10220948

Formula: C15H15N5

MW: 265.31

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	265.31
XLogP3	2.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	265.13274550
Monoisotopic Mass	265.13274550
Topological Polar Surface Area	55.1 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	356
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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T9273-01	SI 60
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T207257-01	SI-W052
T35464-01	(±) 14 (15) -EET-SI
T18313-01	Mc-O-Si (di-iso) -Cl
T205797-01	Mc-O-Si (di-iso) -O-Gemcitabine
T17985-01	Gemcitabine-O-Si (di-iso) -O-Mc
TMPH-02152-01	Sucrase-isomaltase/SI Protein, Human, Recombinant (His)
TMPH-03600-01	Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc)

Alternative Products

Catalog	Name
466073-01	SI-2
A8998-5	SI-2 hydrochloride
MBS3617433-01	(E)-SI-2
HY-121582-01	(E) -SI-2
HY-101447A-01	SI-2 (hydrochloride)
E4A10U64	Recombinant Art si 2
HY-101447AR	SI-2 (hydrochloride) (Standard)

SI-2

Chemical Information

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