Org-6906

• Target:

  Others|||Adrenergic Receptor

• Related Pathways:

  Neuroscience|||Others|||GPCR/G Protein

• Bioactivity:

  Tylophorine analog Org-6906 is a potential anticancer and immunosuppressive agent. Org-6906 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. Org-6906 allosterically regulates the ATPase and chaperone activities of HSC70 by promoting ATP hydrolysis in the presence of specific RNA binding motifs (AUUUA) of cyclin D1 mRNA.

• Smiles:

  Cl.[H][C@@]12Cc3ccccc3[C@@]([H])(C1)C=C[C@H]2N

• Molecular Formula:

  C13H16ClN

• Molecular Weight:

  221.73

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  67384-25-2