Org 24598

• Target:

  Others|||GlyT

• Related Pathways:

  Neuroscience|||Others

• Bioactivity:

  Potent and selective inhibitor of the glial glycine transporter GlyT1b (IC50 = 6.9 nM) . Displays negligible activity at GlyT-2, adrenoreceptors, dopamine, 5HT receptors and noradrenaline, dopamine, 5HT and GABA transporters (pIC50 in vivo.

• Smiles:

  [C@@H](OC1=CC=C(C(F)(F)F)C=C1)(CCN(CC(O)=O)C)C2=CC=CC=C2

• Molecular Formula:

  C19H20F3NO3

• Molecular Weight:

  367.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  372198-97-5