C-021

• Target :

  CCR

• Related Pathways :

  GPCR/G Protein|||Immunology/Inflammation|||Microbiology/Virology

• Purity :

  >99.99%

• Bioactivity :

  C 021 dihydrochloride is a potent CCR4 antagonist. C-021 (4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-) dihydrochloride potently inhibits functional chemotaxis in humans and mice with IC50s of 140 nM and 39 nM, respectively. It effectively prevents human CCL22-derived [35S]GTP?S from binding to the receptor (IC50: 18 nM) .

• Smiles :

  N(C=1C2=C(N=C(N1)N3CCC(CC3)N4CCCCC4)C=C(OC)C(OC)=C2)C5CCCCCC5

• Molecular Formula :

  C27H41N5O2

• Molecular Weight :

  467.65

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  864289-85-0