Sym-021

• Target :

  PD-1/PD-L1

• Related Pathways :

  Cell Cycle/Checkpoint|||Immunology/Inflammation|||Apoptosis

• Bioactivity :

  Sym-021 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. It blocks the binding of PD-L1 and PD-L2 ligands, which stimulates the secretion of interferon IFN-? and IL-2 and promotes T cell proliferation. Sym-021 shows antitumor activity in PDX mouse models.

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C