LM-021

• Target :

  Interleukin|||Reactive Oxygen Species|||Dehydrogenase|||Caspase

• Related Pathways :

  Metabolism|||Immunology/Inflammation|||Proteases/Proteasome|||Apoptosis|||NF-?B

• Bioactivity :

  LM-021, a coumarin-chalcone derivative, exhibits properties such as anti-aggregation, antioxidant, neuroprotective, and anti-inflammatory effects. It inhibits the production of nitric oxide (NO), IL-1?, IL-6, and TNF-?, as well as the expression of CD68 and MHCII. Additionally, LM-021 reduces caspase 1 activity, lactate dehydrogenase release, and ROS level elevation. It is used in neurological research.

• Smiles :

  OC=1C=2C(OC(=O)C1C(/C=C/C3=CC=C(N(C)C)C=C3)=O)=CC=CC2

• Molecular Formula :

  C20H17NO4

• Molecular Weight :

  335.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1022282-98-9