Lenalidomide-C9-aldehyde

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  Lenalidomide-C9-aldehyde is a synthesized E3 ligase ligand-linker conjugate that incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-C9-aldehyde can be used in the synthesis of a series of PROTACs, such as INY-03-041. INY-03-041 is a potent, highly selective and PROTAC-based pan-Akt degrader. INY-03-041 inhibits Akt1, Akt2 and Akt3 with IC50s of 2.0 nM, 6.8 nM and 3.5 nM, respectively[1].

• Smiles :

  O=C(C(N(CC1=C2C=CC=C1CCCCCCCCCC=O)C2=O)CC3)NC3=O

• Molecular Formula :

  C23H30N2O4

• Molecular Weight :

  398.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C