Lenalidomide-I

• Target:

  Others|||Ligand for E3 Ligase

• Related Pathways:

  PROTAC|||Others

• Bioactivity:

  Lenalidomide-I (Compound 72) is a derivative of the cereblon (CRBN) ligand, Lenalidomide, with affinity for E3 ubiquitin ligase. It facilitates the recruitment of CRBN protein. Lenalidomide-I can be utilized in PROTACs, such as the PROTAC BET degrader QCA570, by linking it to the targeted protein ligand through a linker.

• Smiles:

  O=C1N (CC=2C1=CC=CC2I) C3C (=O) NC (=O) CC3

• Molecular Formula:

  C13H11IN2O3

• Molecular Weight:

  370.14

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2207541-30-6