Lenalidomide-F

• Target:

  Ligand for E3 Ligase

• Related Pathways:

  PROTAC

• Bioactivity:

  Lenalidomide-F serves as the E3 ligase ligand for LWY713. LWY713 is a PROTAC-based FLT3 degrader (DC50= 0.64 nM) that selectively induces the degradation of FLT3 through a cereblon and proteasome-dependent mechanism.

• Smiles:

  O=C1NC(=O)C(N2C(=O)C=3C=CC=C(F)C3C2)CC1

• Molecular Formula:

  C13H11FN2O3

• Molecular Weight:

  262.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2359705-88-5