Lenalidomide hemihydrate

• Target :

  IKZF|||Molecular Glues|||Apoptosis|||Ligand for E3 Ligase|||TNF

• Related Pathways :

  PROTAC|||Immunology/Inflammation|||Apoptosis

• Purity :

  >99.99%

• Bioactivity :

  Lenalidomide hemihydrate is a derivative of Thalidomide, an orally active immunomodulator that acts as a molecular gel. It is a ligand for the ubiquitin E3 ligase cereblon, which selectively ubiquitinates and degrades two lymphoid transcription factors, IKZF1 and IKZF3, via the CRBN-CRL4 ubiquitin ligase.

• Smiles :

  O=C(C(N(CC1=C2C=CC=C1N)C2=O)CC3)NC3=O.O=C(C(N(CC4=C5C=CC=C4N)C5=O)CC6)NC6=O.[H]O[H]

• Molecular Formula :

  C13H13N3O3.1/2H2O

• Molecular Weight :

  268.28

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  847871-99-2