Lenalidomide hemihydrate

CAT: 0931-MF-0049574Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0049574Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
847871-99-2
Target
IKZF|||Molecular Glues|||Apoptosis|||Ligand for E3 Ligase|||TNF
Related Pathways
PROTAC|||Immunology/Inflammation|||Apoptosis
Purity
>99.99%
Bioactivity
Lenalidomide hemihydrate is a derivative of Thalidomide, an orally active immunomodulator that acts as a molecular gel. It is a ligand for the ubiquitin E3 ligase cereblon, which selectively ubiquitinates and degrades two lymphoid transcription factors, IKZF1 and IKZF3, via the CRBN-CRL4 ubiquitin ligase.
Smiles
O=C(C(N(CC1=C2C=CC=C1N)C2=O)CC3)NC3=O.O=C(C(N(CC4=C5C=CC=C4N)C5=O)CC6)NC6=O.[H]O[H]
Molecular Formula
C13H13N3O3.1/2H2O
Molecular Weight
268.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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