ONO-2952

• Target :

  Others|||Adrenergic Receptor

• Related Pathways :

  Others|||GPCR/G Protein|||Neuroscience

• Bioactivity :

  ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels, and enzymes. ONO-2952 is a potent and selective translocator protein 18 kDa (TSPO) antagonist (Ki: 0.33-9.30 nM for rat and human TSPO) . ONO-2952 has the potential for irritable bowel syndrome treatment. ONO-2952 exerts its anti-stress effects through inhibition of excessive activation of the noradrenergic system in the brain without the amnesic effect.

• Smiles :

  COc1cc(Cl)ccc1[C@@H]1N(CC2(CC2)c2c1[nH]c1cccc(F)c21)C(C)=O

• Molecular Formula :

  C22H20ClFN2O2

• Molecular Weight :

  398.86

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  895169-20-7