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ONO-2952

CAT: 0931-T16393-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T16393-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
895169-20-7
Target
Others, Adrenergic Receptor
Related Pathways
Others, GPCR/G Protein, Neuroscience
Bioactivity
ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels, and enzymes. ONO-2952 is a potent and selective translocator protein 18 kDa (TSPO) antagonist (Ki: 0.33-9.30 nM for rat and human TSPO) . ONO-2952 has the potential for irritable bowel syndrome treatment. ONO-2952 exerts its anti-stress effects through inhibition of excessive activation of the noradrenergic system in the brain without the amnesic effect.
Smiles
COc1cc(Cl)ccc1[C@@H]1N(CC2(CC2)c2c1[nH]c1cccc(F)c21)C(C)=O
Molecular Formula
C22H20ClFN2O2
Molecular Weight
398.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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