ONO-8711

• Target:

  Prostaglandin Receptor|||Others

• Related Pathways:

  Immunology/Inflammation|||Others|||GPCR/G Protein

• Bioactivity:

  ONO-8711 is a potent and selective competitive antagonist of the EP1 receptor, with Ki values of 0.6 nM for human EP1 and 1.7 nM for mouse EP1. It effectively reduces tumor incidence and multiplicity in mouse models of colon, breast, and oral cancer [1].

• Smiles:

  C(NS(=O)(=O)C1=C(C)C=C(Cl)C=C1)[C@@H]2[C@@H](/C=C\CCCC(O)=O)C3CCC2CC3

• Molecular Formula:

  C22H30ClNO4S

• Molecular Weight:

  440

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  216158-34-8