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ONO-8711

CAT: 0931-T22125-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T22125-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
216158-34-8
Target
Prostaglandin Receptor|||Others
Related Pathways
Immunology/Inflammation|||Others|||GPCR/G Protein
Bioactivity
ONO-8711 is a potent and selective competitive antagonist of the EP1 receptor, with Ki values of 0.6 nM for human EP1 and 1.7 nM for mouse EP1. It effectively reduces tumor incidence and multiplicity in mouse models of colon, breast, and oral cancer [1].
Smiles
C(NS(=O)(=O)C1=C(C)C=C(Cl)C=C1)[C@@H]2[C@@H](/C=C\CCCC(O)=O)C3CCC2CC3
Molecular Formula
C22H30ClNO4S
Molecular Weight
440
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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