ONO-2920632

CAT: 0931-T205012-01Size: 10 mgDry Ice: NoHazardous: No
CAT#: T205012-01Size: 10 mg
Selected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2230296-66-7
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
ONO-2920632 is an orally active and CNS-penetrant TREK channel activator with EC50 values of 0.3?µM for TREK-1 and 2.8?µM for TREK-2. It demonstrates selectivity for other K2P channels, showing over 91-fold selectivity against TASK1, TASK2, TASK3, TRAAK, TWIK2, and 31-fold selectivity against TRESK. ONO-2920632 exhibits analgesic effects and is used in the study of pain, migraine, and neurological disorders.
Smiles
O=C(NCC1=CC=C(OC(F)(F)F)C=C1F)C=2C=CC3=NC=NN3C2
Molecular Formula
C15H10F4N4O2
Molecular Weight
354.259
Shipping Conditions
Cool pack
Storage Temperature
-20°C