GNE-618

• Target :

  NAMPT

• Related Pathways :

  Metabolism

• Bioactivity :

  GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM) . GNE-618 depletes NAD levels and induces tumor cell death. It has anti-tumor activity.

• Smiles :

  FC(F)(F)c1cccc(c1)S(=O)(=O)c1ccc(CNC(=O)c2cnc3[nH]ncc3c2)cc1

• Molecular Formula :

  C21H15F3N4O3S

• Molecular Weight :

  460.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1362151-42-5