GNE-618

• Target:

  NAMPT

• Related Pathways:

  Metabolism

• Bioactivity:

  GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM) . GNE-618 depletes NAD levels and induces tumor cell death. It has anti-tumor activity.

• Smiles:

  FC (F) (F) c1cccc (c1) S (=O) (=O) c1ccc (CNC (=O) c2cnc3[nH]ncc3c2) cc1

• Molecular Formula:

  C21H15F3N4O3S

• Molecular Weight:

  460.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1362151-42-5