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AC-73

CAT: 0931-T14091-05Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T14091-05Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
775294-71-8
Target
Autophagy
Related Pathways
Autophagy
Purity
0.9936
Bioactivity
AC-73 is an orally available Cluster of Differentiation 147 (CD147) inhibitor with high bioavailability that selectively disrupts the dimerization of CD147 (the binding site is in the N-terminal IgC2 domain of CD147 including Glu64 and Glu73), resulting in inhibition of the CD147/ERK1/2/STAT3/MMP-2 pathway and inhibition of liver cancer cell motility and invasion. AC-73 has antiproliferative activity and induces autophagy in leukemia cells.
Smiles
OC(CNCc1ccc(cc1)-c1ccccc1)c1cccc(O)c1
Molecular Formula
C21H21NO2
Molecular Weight
319.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

3-(1-Hydroxy-2-((4-phenylphenyl)methylamino)ethyl)phenol
CAS Number775294-71-8
PubChem CID2989791
IUPAC Name3-[1-hydroxy-2-[(4-phenylphenyl)methylamino]ethyl]phenol
Molecular FormulaC21H21NO2
Molecular Weight319.4
XLogP2.8
Topological Polar Surface Area52.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count6
Heavy Atom Count24
Formal Charge0
Complexity348
SMILES
C1=CC=C(C=C1)C2=CC=C(C=C2)CNCC(C3=CC(=CC=C3)O)O
InChI
InChI=1S/C21H21NO2/c23-20-8-4-7-19(13-20)21(24)15-22-14-16-9-11-18(12-10-16)17-5-2-1-3-6-17/h1-13,21-24H,14-15H2
InChIKey
UECKKYNEEBRMIL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-(1-Hydroxy-2-((4-phenylphenyl)methylamino)ethyl)phenol
CAS: 775294-71-8
CID: 2989791
Formula: C21H21NO2
MW: 319.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight319.4
XLogP32.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count6
Exact Mass319.157228913
Monoisotopic Mass319.157228913
Topological Polar Surface Area52.5 Ų
Heavy Atom Count24
Formal Charge0
Complexity348
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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