AC-73

• Description:

  AC-73 is an orally available Cluster of Differentiation 147 (CD147) inhibitor with high bioavailability that selectively disrupts the dimerization of CD147 (the binding site is in the N-terminal IgC2 domain of CD147 including Glu64 and Glu73), resulting in inhibition of the CD147/ERK1/2/STAT3/MMP-2 pathway and inhibition of liver cancer cell motility and invasion. AC-73 has antiproliferative activity and induces autophagy in leukemia cells.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  319.4

• Molecular Formula:

  C21H21NO2

• Notes:

  Research use only, not for human use.

• Receptor:

  Autophagy

• CAS Number:

  775294-71-8