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AC-73

CAT: 0931-T14091-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T14091-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
775294-71-8
Target
Autophagy
Related Pathways
Autophagy
Purity
0.9936
Bioactivity
AC-73 is an orally available Cluster of Differentiation 147 (CD147) inhibitor with high bioavailability that selectively disrupts the dimerization of CD147 (the binding site is in the N-terminal IgC2 domain of CD147 including Glu64 and Glu73), resulting in inhibition of the CD147/ERK1/2/STAT3/MMP-2 pathway and inhibition of liver cancer cell motility and invasion. AC-73 has antiproliferative activity and induces autophagy in leukemia cells.
Smiles
OC(CNCc1ccc(cc1)-c1ccccc1)c1cccc(O)c1
Molecular Formula
C21H21NO2
Molecular Weight
319.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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