AC-73

• Target:

  Autophagy

• Related Pathways:

  Autophagy

• Purity:

  0.9936

• Bioactivity:

  AC-73 is an orally available Cluster of Differentiation 147 (CD147) inhibitor with high bioavailability that selectively disrupts the dimerization of CD147 (the binding site is in the N-terminal IgC2 domain of CD147 including Glu64 and Glu73), resulting in inhibition of the CD147/ERK1/2/STAT3/MMP-2 pathway and inhibition of liver cancer cell motility and invasion. AC-73 has antiproliferative activity and induces autophagy in leukemia cells.

• Smiles:

  OC(CNCc1ccc(cc1)-c1ccccc1)c1cccc(O)c1

• Molecular Formula:

  C21H21NO2

• Molecular Weight:

  319.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  775294-71-8