Products for Research Use Only
RegisterLogin

Alpha-Mangostin

CAT: 0804-HY-N0328-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0328-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
CAS Number
6147-11-1
Product Name Alternative
α-Mangostin
UNSPSC
12352005
Hazard Statement
H301
Target
Apoptosis; Bacterial; Fungal; Reactive Oxygen Species (ROS) ; Virus Protease
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alpha-Mangostin.html
Concentration
10mM
Purity
99.31
Solubility
DMSO : 110 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
O=C1C2=C(OC3=C1C(C/C=C(C)\C)=C(OC)C(O)=C3)C=C(O)C(C/C=C(C)\C)=C2O
Molecular Formula
C24H26O6
Molecular Weight
410.46
Precautions
H301
References & Citations
[1]Kim HJ, et al. Discovery of α-mangostin as a novel competitive inhibitor against mutant isocitrate dehydrogenase-1. Bioorg Med Chem Lett. 2015 Dec 1;25 (23) :5625-31.|[2]Lee HN, et al. Antitumor and apoptosis-inducing effects of α-mangostin extracted from the pericarp of the mangosteen fruit (Garcinia mangostana L.) in YD-15 tongue mucoepidermoid carcinoma cells. Int J Mol Med. 2016 Apr;37 (4) :939-48.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 2

Related Products

CatalogName
HY-N1957-01Gamma-Mangostin
HY-N0941-01Beta-Mangostin
HY-N0941RBeta-Mangostin (Standard)
HY-N1957RGamma-Mangostin (Standard)
HY-B0141A-01Alpha-Estradiol
HY-W087913-01Alpha-Naphtholphthalein
HY-154535Alpha-inosine
HY-154534-01Alpha-Adenosine
HY-P5172MitTx-alpha
HY-154536-01Alpha-Guanosine

Alternative Products

CatalogName
6856/10alpha-Mangostin
328054Alpha-Mangostin, 98%
328053Alpha-Mangostin, 95%
TB0924-0025α-Mangostin
MBS578105Mangostin
GTR19174063-01A-Mangostin
S0939-5mgγ-Mangostin

Popular Products