Alpha-Estradiol

CAT: 0804-HY-B0141A-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0141A-01Size:100 mg
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Description
Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.
CAS Number
[57-91-0]
Product Name Alternative
Alfatradiol; Epiestradiol; Epiestrol
UNSPSC
12352005
Hazard Statement
H341, H351, H360, H362, H410
Target
5 alpha Reductase; Bacterial; Endogenous Metabolite
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Alpha-Estradiol.html
Purity
99.88
Solubility
DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 11.11 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])CC2
Molecular Formula
C18H24O2
Molecular Weight
272.39
Precautions
H341, H351, H360, H362, H410
References & Citations
[1]Schriefers H, et al. Inhibition of testosterone metabolism by 17-alpha-estradiol in rat liver slices. Arzneimittelforschung. 1991 Nov;41 (11) :1186-9.|[2]Santos RS, et al. The effects of 17 alpha-estradiol to inhibit inflammation in vitro. Biol Sex Differ. 2017 Sep 6;8:30.|[3]Zhang HB, et al. 17-Alpha-estradiol ameliorating oxygen-induced retinopathy in a murine model. Jpn J Ophthalmol. 2012 Jul;56 (4) :407-15.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite

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