Alpha-Adenosine

• Description:

  Alpha-Adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/alpha-adenosine.html

• Purity:

  99.91

• Solubility:

  DMSO : 250 mg/mL (ultrasonic)

• Smiles:

  O[C@@H]1[C@H] (O) [C@@H] (CO) O[C@@H]1N (C=N2) C3=C2C (N) =NC=N3

• Molecular Formula:

  C10H13N5O4

• Molecular Weight:

  267.24

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  No Development Reported

• CAS Number:

  5682-25-7