KDOAM-25

• Target:

  Histone Demethylase|||Antibacterial

• Related Pathways:

  Microbiology/Virology|||Chromatin/Epigenetic

• Bioactivity:

  KDOAM-25, a potent and highly selective inhibitor of histone lysine demethylases 5 (KDM5) with IC50 values of 71 nM for KDM5A, 19 nM for KDM5B, 69 nM for KDM5C, and 69 nM for KDM5D, enhances global H3K4 methylation at transcriptional start sites and reduces proliferation in multiple myeloma MM1S cells.

• Smiles:

  C (NCC (N (CCN (C) C) CC) =O) C1=CC (C (N) =O) =CC=N1

• Molecular Formula:

  C15H25N5O2

• Molecular Weight:

  307.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2230731-99-2