CL2-SN-38

• Target:

  Drug-Linker Conjugates for ADC

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  CL2-SN-38, a part of the antibody-drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. SN-38 is an inhibitor of DNA topoisomerase I.

• Smiles:

  CCc1c2Cn3c (cc4c (COC (=O) [C@@]4 (CC) OC (=O) OCc4ccc (NC (=O) [C@H] (CCCCN) NC (=O) [C@H] (Cc5ccccc5) NC (=O) COCC (=O) NCCOCCOCCOCCOCCOCCOCCOCCOCCn5cc (CNC (=O) C6CCC (CN7C (=O) C=CC7=O) CC6) nn5) cc4) c3=O) -c2nc2ccc (O) cc12

• Molecular Formula:

  C82H106N12O23

• Molecular Weight:

  1627.79

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1036969-20-6