Afatinib D6

• Target:

  Autophagy|||EGFR

• Related Pathways:

  JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Autophagy

• Bioactivity:

  Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.

• Smiles:

  N(C=1C2=C(C=C(O[C@H]3CCOC3)C(NC(/C=C/CN(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4

• Molecular Formula:

  C24H25ClFN5O3

• Molecular Weight:

  491.98

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1313874-96-2