Afatinib Dimaleate

• Target :

  Apoptosis|||p38 MAPK|||Akt|||c-Met/HGFR|||HER|||Autophagy|||EGFR

• Related Pathways :

  Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Autophagy|||JAK/STAT signaling|||Cytoskeletal Signaling|||Apoptosis|||MAPK

• Purity :

  >99.99%

• Bioactivity :

  Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity.

• Smiles :

  OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1

• Molecular Formula :

  C32H33ClFN5O11

• Molecular Weight :

  718.08

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  850140-73-7