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CycLuc1

CAT: 0804-HY-111653-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111653-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging[1][2].
CAS Number
1247879-16-8
UNSPSC
12171500
Hazard Statement
H302, H315, H319
Target
Reactive Oxygen Species (ROS)
Type
Dye Reagents
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/CycLuc1.html
Purity
99.72
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C([C@@H]1N=C(C2=NC3=CC4=C(NCC4)C=C3S2)SC1)O
Molecular Formula
C13H11N3O2S2
Molecular Weight
305.38
Precautions
H302, H315, H319
References & Citations
[1]Shiv K, et al. Abstract 4112: Synthetic luciferin, CycLuc1, improves bioluminescence imaging for intracranial glioblastoma xenografts. 10.1158/1538-7445.AM2018-4112|[2]Evans MS, et al. A synthetic luciferin improves bioluminescence imaging in live mice. Nat Methods. 2014 Apr;11 (4) :393-5. doi: 10.1038/nmeth.2839. Epub 2014 Feb 9. Erratum in: Nat Methods. 2014 Apr;11 (4) :395.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported