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Oligomycin E

CAT: 0804-HY-125300-01Size: 1 mgDry Ice: NoHazardous: No
CAT#: HY-125300-01Size: 1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oligomycin E is a antitumor antibiotic that can be isolated from Streptomyces. Oligomycin E has significant antifungal activity, showing minimal inhibitory concentrations (MICs) values between 2 and 75μg/mL. Oligomycin E has strong antitumor activity against HeLa cells, with an IC50 of 0.014 μg/mL[1].
CAS Number
[110231-34-0]
UNSPSC
12352005
Target
Antibiotic; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oligomycin-e.html
Solubility
10 mM in DMSO
Smiles
O=C(/C=C/[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)[C@@H](O)[C@@H]1C)=O)O[C@@]([C@@H]2C)([H])[C@@](C)(O)[C@@]3(C(C[C@H](C)[C@H](C[C@H](O)C)O3)=O)O[C@@]2([H])CC[C@@H](CC)/C=C/C=C/C[C@@H](C)[C@H](O)[C@@](C)(O)C1=O
Molecular Formula
C45H72O13
Molecular Weight
821.05
References & Citations
[1]Kobayashi K, et al. Oligomycin E, a new antitumor antibiotic produced by Streptomyces sp. MCI-2225. J Antibiot (Tokyo) . 1987 Jul;40 (7) :1053-7.|[2]Khebizi N, et al. Oligomycins A and E, major bioactive secondary metabolites produced by Streptomyces sp. strain HG29 isolated from a Saharan soil. J Mycol Med. 2018 Mar;28 (1) :150-160.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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