Oligomycin D

• Description:

  Oligomycin D (Rutamycin A) is an antibiotic. Oligomycin D can be derived from a strain of S. rutgersensis. Oligomycin D also is a potent inhibitors of K-Ras PM localization. Oligomycin D can be used for the research of various cancers[1].

• Product Name Alternative:

  Rutamycin A

• UNSPSC:

  12352005

• Target:

  Antibiotic; Ras

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; GPCR/G Protein; MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/oligomycin-d.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@H](O)C[C@H]1[C@H](CC[C@]2(O1)C[C@H](OC(/C=C/[C@@H]([C@H]([C@@H](C([C@@H]([C@H]([C@@H]3C)O)C)=O)C)O)C)=O)[C@@]([C@H](CC[C@@](CC)(/C=C/C=C/C[C@H]([C@@H]([C@@](C3=O)(C)O)O)C)[H])O2)(C)[H])C

• Molecular Formula:

  C44H72O11

• Molecular Weight:

  777.04

• References & Citations:

  [1]Salim AA, et al. Oligomycins as inhibitors of K-Ras plasma membrane localisation. Org Biomol Chem. 2016 Jan 14;14 (2) :711-715.|[2]Salim AA, et al. Oligomycins as inhibitors of K-Ras plasma membrane localisation. Org Biomol Chem. 2016 Jan 14;14 (2) :711-715.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1404-59-7]