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Oligomycin D

CAT: 0804-HY-125335Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-125335Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oligomycin D (Rutamycin A) is an antibiotic. Oligomycin D can be derived from a strain of S. rutgersensis. Oligomycin D also is a potent inhibitors of K-Ras PM localization. Oligomycin D can be used for the research of various cancers[1].
CAS Number
1404-59-7
Product Name Alternative
Rutamycin A
UNSPSC
12352005
Target
Antibiotic; Ras
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oligomycin-d.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](O)C[C@H]1[C@H](CC[C@]2(O1)C[C@H](OC(/C=C/[C@@H]([C@H]([C@@H](C([C@@H]([C@H]([C@@H]3C)O)C)=O)C)O)C)=O)[C@@]([C@H](CC[C@@](CC)(/C=C/C=C/C[C@H]([C@@H]([C@@](C3=O)(C)O)O)C)[H])O2)(C)[H])C
Molecular Formula
C44H72O11
Molecular Weight
777.04
References & Citations
[1]Salim AA, et al. Oligomycins as inhibitors of K-Ras plasma membrane localisation. Org Biomol Chem. 2016 Jan 14;14 (2) :711-715.|[2]Salim AA, et al. Oligomycins as inhibitors of K-Ras plasma membrane localisation. Org Biomol Chem. 2016 Jan 14;14 (2) :711-715.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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