Oligomycin C

• Description :

  Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Antibiotic; Fungal

• Type :

  Natural Products

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/oligomycin-c.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@@H]([C@H]([C@@H](C([C@H]([C@H]([C@@H](C/C=C/C=C/[C@@]([H])(CC[C@]1([C@H]([C@@]([H])(O2)[C@@H]([C@]3(O1)CC[C@@H]([C@@]([H])(O3)C[C@@H](C)O)C)C)C)[H])CC)C)O)C)=O)C)O)C)[C@H]([C@@H]([C@H](/C=C/C2=O)C)O)C

• Molecular Formula :

  C45H74O10

• Molecular Weight :

  775.06

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Yang PW, et al. Oligomycins A and C, major secondary metabolites isolated from the newly isolated strain Streptomyces diastaticus. Folia Microbiol (Praha) . 2010;55 (1) :10-16.|[2]Han S, et al. Functional characterization of CYP107W1 from Streptomyces avermitilis and biosynthesis of macrolide oligomycin A. Arch Biochem Biophys. 2015;575:1-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  Macrolide

• CAS Number :

  [11052-72-5]