PROTAC BRD4-DCAF1 degrader-1

PROTAC BRD4-DCAF1 degrader-1

• CAS Number: 3036944-87-0
• UNSPSC Description: PROTAC BRD4-DCAF1 degrader-1 (I-907) is a BRD4-DCAF1 PROTAC degrader, DC50 is 10~100 nM. (Pink: BRD4-DCAF1 ligand (HY-169152); Black: linker (HY-126976); Blue: E3 ligase ligand (HY-15846))[1].
• Target Antigen: Epigenetic Reader Domain; PROTACs
• Type: Reference compound
• Related Pathways: Epigenetics;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-brd4-dcaf1-degrader-1.html
• Smiles: CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(NCCOCCOCCOCCOCCOCCCC4=CC=C(C=C4)C(C5=C(C6=C(C(F)=CC=C6F)C)C(C(N[C@H](C7=CC(Cl)=CC=C7)CC(N)=O)=O)=CN5)=O)=O)C8=NN=C(C)N28
• Molecular Weight: 1182.17
• References & Citations: [1]Lewis Dale Pennington, et al. Protein degraders and uses thereof. WO2024092009A1. 2024-05-02.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported