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R9BP rabbit pAb

CAT: 0855-ES13828-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES13828-01Size:50 µL
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Background
The protein encoded by this gene functions as a regulator of G protein-coupled receptor signaling in phototransduction. Studies in bovine and mouse show that this gene is expressed only in the retina, and is localized in the rod outer segment membranes. This protein is associated with a heterotetrameric complex, specifically interacting with the regulator of G-protein signaling 9, and appears to function as the membrane anchor for the other largely soluble interacting partners. Mutations in this gene are associated with prolonged electroretinal response suppression (PERRS), also known as bradyopsia. [provided by RefSeq, Mar 2010]
Description
The protein encoded by this gene functions as a regulator of G protein-coupled receptor signaling in phototransduction. Studies in bovine and mouse show that this gene is expressed only in the retina, and is localized in the rod outer segment membranes. This protein is associated with a heterotetrameric complex, specifically interacting with the regulator of G-protein signaling 9, and appears to function as the membrane anchor for the other largely soluble interacting partners. Mutations in this gene are associated with prolonged electroretinal response suppression (PERRS), also known as bradyopsia. [provided by RefSeq, Mar 2010],
UniProt
Q6ZS82
Swiss Prot
Q6ZS82
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human R9BP AA range: 138-188
Target
R9BP
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Membrane ; Single-pass type IV membrane protein .
Gene ID (Human)
388531

UniProtKB · Q6ZS82

Regulator of G protein signaling 9-binding protein

R9BP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6ZS82
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RGS9BP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6ZVJ6
Protein keywords

Domain

Coiled coilTransmembraneTransmembrane helix

Cellular component

Membrane

Technical term

Proteomics identificationReference proteome

Biological process

Sensory transductionVision

Molecular function

Signal transduction inhibitor

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