Products for Research Use Only
RegisterLogin

EPI-7170

CAT: 0804-HY-150102-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-150102-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
EPI-7170, a ralaniten analogue, is a potent androgen receptor N-terminal structural domain antagonist that blocks the transcriptional activity of full-length AR (FL-AR) and AR splice variants (AR-Vs) . EPI-7170 has antitumor effects against enzalutamide resistant castration-resistant prostate cancer (CRPC) [1].
CAS Number
2139288-26-7
UNSPSC
12352005
Target
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/epi-7170.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=CC(Cl)=C(C(Cl)=C1)OC[C@H](O)CCl)(C2=CC=C(C=C2)OC[C@H](O)CNS(C)(=O)=O)C
Molecular Formula
C22H28Cl3NO6S
Molecular Weight
540.88
References & Citations
[1]Hirayama Y, et al. Combination therapy with androgen receptor N-terminal domain antagonist EPI-7170 and enzalutamide yields synergistic activity in AR-V7-positive prostate cancer. Mol Oncol. 2020 Oct;14 (10) :2455-2470.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N1286825-Epi-28-epi-cyasterone
HY-N11269Epi-β-amyrin
HY-W016509-01Epi-Inositol
HY-100348-01EPI-001
HY-135154Epi-Aszonalenin A
HY-16772-01EPI-743
HY-136968Epi-Doramectin
HY-N3828Epi-Eriocalyxin A
HY-N7265Epi-galantamine
HY-N6711AEpi-Equisetin

Alternative Products

CatalogName
BA9181-10EPI-7170
CS-O-4490517-epi-10-epi-Nandrolone
TN7917-0125-Epi-28-epi-cyasterone
NBP3-14079PCPMouse Monoclonal Catalase Antibody (HPYL/7170) [PerCP]
NBP3-14079BMouse Monoclonal Catalase Antibody (HPYL/7170) [Biotin]
MBS6006559-01Salvinorin, Epi-demethyl (Epi-demethyl Salvinorin A)
BA7671-25epi-Inositol
T13681-01Epi-galantamine
TP2690-01EPI-X4
448288-01Epi Dienogest

Popular Products