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Epi-Eriocalyxin A

CAT: 0804-HY-N3828Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3828Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Epi-Eriocalyxin A (Epieriocalyxin A), a diterpenoid isolated from Isodon eriocalyx, induces colon cancer apoptosis. epi-Eriocalyxin A also inhibits ERK1/2 and JNK activation, which suppresses Bcl-2 expression[1].
CAS Number
191545-24-1
UNSPSC
12352005
Target
Apoptosis; ERK; JNK
Type
Natural Products
Related Pathways
Apoptosis; MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/epi-eriocalyxin-a.html
Solubility
10 mM in DMSO
Smiles
O=C[C@H](C1(C)C)[C@@](COC2=O)(C(C=C1)=O)[C@@]3([H])[C@]2(C([C@@H]4C)=O)C[C@H]4CC3
Molecular Formula
C20H24O5
Molecular Weight
344.40
References & Citations
[1]Zhou Wang, et al. Epieriocalyxin A Induces Cell Apoptosis Through JNK and ERK1/2 Signaling Pathways in Colon Cancer Cells. Cell Biochem Biophys. 2015 Nov;73 (2) :559-564.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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