CGP 31358

CAT: 0804-HY-120524Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-120524Size:1 Each
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Description
CGP 31358 is an anticonvulsant agent that binds to a site on the NMDA receptor complex that is coupled to both the transmitter recognition site and to the channel domain. CGP 31358 inhibits the binding of L-Glutamate to the NMDA receptor complex with an IC50 of 53 μM[1].
CAS Number
[125652-47-3]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cgp-31358.html
Smiles
O=C(C1=NN(C2=CC=C(C(C)(C3=CC=C(Cl)C=C3)C)C=C2OC)C=N1)N
Molecular Formula
C19H19ClN4O2
Molecular Weight
370.83
References & Citations
[1]J Baud, et al. CGP 31358 binds to a site on the NMDA receptor that is coupled to both the transmitter recognition site and the channel domain. Neurosci Lett. 1989 Dec 15;107 (1-3) :184-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor

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