CGP 31358

• Description :

  CGP 31358 is an anticonvulsant agent that binds to a site on the NMDA receptor complex that is coupled to both the transmitter recognition site and to the channel domain. CGP 31358 inhibits the binding of L-Glutamate to the NMDA receptor complex with an IC50 of 53 μM[1].

• UNSPSC :

  12352005

• Target :

  IGluR

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/cgp-31358.html

• Smiles :

  O=C(C1=NN(C2=CC=C(C(C)(C3=CC=C(Cl)C=C3)C)C=C2OC)C=N1)N

• Molecular Formula :

  C19H19ClN4O2

• Molecular Weight :

  370.83

• References & Citations :

  [1]J Baud, et al. CGP 31358 binds to a site on the NMDA receptor that is coupled to both the transmitter recognition site and the channel domain. Neurosci Lett. 1989 Dec 15;107 (1-3) :184-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  NMDA Receptor

• CAS Number :

  [125652-47-3]