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Certolizumab pegol

CAT: 0804-HY-P9953-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P9953-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Certolizumab pegol (Certolizumab) is a recombinant, polyethylene glycosylated, antigen-binding fragment of a humanized monoclonal antibody that selectively targets and neutralizes tumour necrosis factor-α (TNF-α) . Certolizumab pegol can be used for rheumatoid arthritis and Crohn disease research[1][2].
CAS Number
428863-50-7
Product Name Alternative
Certolizumab; CDP870
UNSPSC
12352203
Target
TNF Receptor
Type
Inhibitory Antibodies
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/certolizumab-pegol.html
Purity
99.30
Solubility
H2O
Smiles
[Certolizumabpegol]
Molecular Weight
(91 kDa)
References & Citations
[1]Deeks ED. Certolizumab pegol: a review of its use in the management of rheumatoid arthritis. Drugs. 2013 Jan;73 (1) :75-97.|[2]Nesbitt A, et al. Mechanism of action of certolizumab pegol (CDP870) : in vitro comparison with other anti-tumor necrosis factor alpha agents. Inflamm Bowel Dis. 2007 Nov;13 (11) :1323-32.|[3]Kosekli MA, et al. Effects of Certolizumab on Cerulein-Induced Acute Pancreatitis in Rats. Pancreas. 2016 Sep;45 (8) :1120-5.
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4°C for 2 years, do not freeze
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched
Isoform
TNFRSF5/CD40

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