Umedaptanib pegol

• Description:

  Umedaptanib pegol is an anti-fibroblast growth factor-2 (FGF2) aptamer. It is used for the study of neovascular age-related macular degeneration (nAMD) .

• Product Name Alternative:

  RBM-007

• UNSPSC:

  12352208

• Target:

  FGFR

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Field of Research:

  Others

• Smiles:

  [Umedaptanibpegol]

• References & Citations:

  [1]Pereira DS, Akita K, Bhisitkul RB, et al. Safety and tolerability of intravitreal umedaptanib pegol (anti-FGF2) for neovascular age-related macular degeneration (nAMD) : a phase 1, open-label study. Eye (Lond) . 2024;38 (6) :1149-1154.|[2]Matsuda Y, Nonaka Y, Futakawa S, et al. Anti-Angiogenic and Anti-Scarring Dual Action of an Anti-Fibroblast Growth Factor 2 Aptamer in Animal Models of Retinal Disease. Mol Ther Nucleic Acids. 2019;17:819-828.|[3]Kimura T, Bosakova M, Nonaka Y, et al. An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice. Sci Transl Med. 2021;13 (592) :eaba4226.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  Phase 2

• CAS Number:

  2734771-59-4