(+) -U-50488 (hydrochloride)

• Description:

  (+) -U-50488 (hydrochloride) (+) -Trans- (1R,2R) -U-50488 hydrochloride) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-) -Trans- (1S,2S) -U-50488 (HY-15997) [1].

• Product Name Alternative:

  (+) -Trans- (1R,2R) -U-50488 (hydrochloride)

• UNSPSC:

  12352005

• Target:

  Opioid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/plus-u-50488-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N(C)[C@H]1[C@H](N2CCCC2)CCCC1)CC3=CC=C(Cl)C(Cl)=C3.[H]Cl

• Molecular Formula:

  C19H27Cl3N2O

• Molecular Weight:

  405.79

• References & Citations:

  [1]DeCosta B, et al. Synthesis and absolute configuration of optically pure enantiomers of a kappa-opioid receptor selective agonist. FEBS Lett. 1987;223 (2) :335-339.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [114528-81-3]