(+) -U-50488 (hydrochloride)

• Description :

  (+) -U-50488 (hydrochloride) (+) -Trans- (1R,2R) -U-50488 hydrochloride) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-) -Trans- (1S,2S) -U-50488 (HY-15997) [1].

• CAS Number :

  [114528-81-3]

• Product Name Alternative :

  (+) -Trans- (1R,2R) -U-50488 (hydrochloride)

• UNSPSC :

  12352005

• Target :

  Opioid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/plus-u-50488-hydrochloride.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N(C)[C@H]1[C@H](N2CCCC2)CCCC1)CC3=CC=C(Cl)C(Cl)=C3.[H]Cl

• Molecular Formula :

  C19H27Cl3N2O

• Molecular Weight :

  405.79

• References & Citations :

  [1]DeCosta B, et al. Synthesis and absolute configuration of optically pure enantiomers of a kappa-opioid receptor selective agonist. FEBS Lett. 1987;223 (2) :335-339.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported