U-89843A (hydrochloride)

• UNSPSC Description:

  U-89843A is an allosteric modulator of GABAA receptor. U-89843A enhances GABA-induced Cl- currents[1].

• Target Antigen:

  GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/u-89843a-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN1C(C)=CC2=C(N3CCCC3)N=C(N4CCCC4)N=C21.[H]Cl

• Molecular Weight:

  321.85

• References & Citations:

  [1]Im HK, Im WB, et al. U-89843A is a novel allosteric modulator of gamma-aminobutyric acidA receptors. J Pharmacol Exp Ther. 1995 Dec;275(3):1390-5.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  157013-85-9