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CypK

CAT: 0804-HY-134669-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-134669-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CypK (N-Cyclopropene-L-Lysine), a cyclopropene derivative of lysine, is efficiently incorporated into antibodies through genetic-code expansion. CypK is a minimal bioorthogonal handle for the creation of stable therapeutic protein conjugates[1][2].
CAS Number
1610703-09-7
Product Name Alternative
N-Cyclopropene-L-Lysine
UNSPSC
12352211
Target
Amino Acid Derivatives
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cypk.html
Purity
98.30
Smiles
N[C@@H](CCCCNC(OCC1C(C)=C1)=O)C(O)=O
Molecular Formula
C12H20N2O4
Molecular Weight
256.30
References & Citations
[1]Oller-Salvia B. Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction. J Vis Exp. 2018 Sep 14; (139) :58066.|[2]Oller-Salvia B, et, al. Rapid and Efficient Generation of Stable Antibody-Drug Conjugates via an Encoded Cyclopropene and an Inverse-Electron-Demand Diels-Alder Reaction. Angew Chem Int Ed Engl. 2018 Mar 5;57 (11) :2831-2834.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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