CypD-IN-29

CAT: 0804-HY-136804Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-136804Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CypD-IN-29 (compound 29) is an inhibitor of the Alzheimer's disease target CypD (KD=88.2 nM) . CypD is a mitochondrial-specific cyclophilin that can bind to β-amyloid protein in brain mitochondria and promote the formation of mitochondrial permeability transition pore (mPTP) .
CAS Number
[1115335-95-9]
UNSPSC
12352005
Target
Cyclophilin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cypd-in-29.html
Smiles
O=C(NCC1=CC=C(F)C=C1)C2=CC=CC(N3C=CN=C3SCC(NC4=CC=CC=C4C#N)=O)=C2
Molecular Formula
C26H20FN5O2S
Molecular Weight
485.53
References & Citations
[1]Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in Aβ-induced mitochondrial dysfunction
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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