Products for Research Use Only
RegisterLogin

CypE-IN-1

CAT: 0804-HY-151489Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-151489Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CypE-IN-1 is a potent and subtype-selective cyclophilin E (CypE) inhibitor. CypE-IN-1 has CypE affinity with IC50 and Ki values of 0.013 μM and 0.072 μM, respectively. CypE-IN-1 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes[1].
CAS Number
3023438-33-4
UNSPSC
12352005
Target
Cyclophilin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cype-in-1.html
Solubility
10 mM in DMSO
Smiles
[H]C(C1=C(C=C(C=C1)C2=CC=C(C=C2)C[C@@H]3NC([C@@]4(CCCN(C(/C=C/C(NCC[C@H](NC(CC5=C(CNC3=O)C=CC=C5)=O)C(N)=O)=O)=O)C4)CC6=CC=CC=C6)=O)B(O)O)=O
Molecular Formula
C46H49BN6O9
Molecular Weight
840.73
References & Citations
[1]Alexander A Peterson, et al. Discovery and molecular basis of subtype-selective cyclophilin inhibitors. Nat Chem Biol. 2022 Sep 26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cyclophilin A; Cyclophilin B; Cyclophilin C; Cyclophilin D; Cyclophilin E; Cyclophilin G

Related Products

CatalogName
HY-173265CypB-IN-1
HY-P10841CyPep-1
HY-170997CypA ligand-1
HY-134669-01CypK
HY-N6838-011,1,1,1-Kestohexaose
HY-151488CypD-IN-4
HY-179416CypD-IN-6
HY-116095CypD-IN-5
HY-157129AMPK-α1β1γ1 activator 1
HY-1336231,1,1-Tribromoacetone

Alternative Products

CatalogName
T74965-01CypE-IN-1
GTR18016793CypE Antibody
MBS1333875-01Recombinant Dictyostelium discoideum Peptidyl-prolyl cis-trans isomerase cypE (cypE)
abx334299-01Peptidylprolyl Isomerase E / CYPE (PPIE) Antibody
abx336965-01Peptidylprolyl Isomerase E / CYPE (PPIE) Antibody (FITC)
abx073508-01Human Peptidylprolyl Isomerase E / CYPE (PPIE) Enzyme
abx336964-01Peptidylprolyl Isomerase E / CYPE (PPIE) Antibody (HRP)
abx336966-01Peptidylprolyl Isomerase E / CYPE (PPIE) Antibody (Biotin)
abx068459-01Mouse Peptidylprolyl Isomerase E / CYPE (PPIE) Protein
abx068458-01Human Peptidylprolyl Isomerase E / CYPE (PPIE) Protein

Popular Products