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PD 118440

CAT: 0804-HY-118706Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118706Size:1 Each
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Description
PD 118440 is an orally active dopamine (DA) agonist. PD 118440 has significant central nervous system effects, including inhibition of striatal DA synthesis, suppression of DA neuron firing, and reversal of Reserpine -induced depression in rats[1].
CAS Number
108351-90-2
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pd-118440.html
Smiles
NC1=NC(C2=CCCN(C2)CCC)=CS1
Molecular Formula
C11H17N3S
Molecular Weight
223.34
References & Citations
[1]Jaen J C, et al. 4- (1, 2, 5, 6-Tetrahydro-1-alkyl-3-pyridinyl) -2-thiazolamines: a novel class of compounds with central dopamine agonist properties[J]. Journal of medicinal chemistry, 1990, 33 (1) : 311-317.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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